Modulating Amygdala–Hippocampal Network Communication: A Potential Therapy for Neuropsychiatric Disorders

Modulating Neuroinflammation to Treat Neuropsychiatric Disorders

Neuroinflammation is recognised as one of the potential mechanisms mediating the onset of a broad range of psychiatric disorders and may contribute to nonresponsiveness to current therapies. Both preclinical and clinical studies have indicated that aberrant inflammatory responses can result in altered behavioral responses and cognitive deficits. In this review, we discuss the role of inflammati...

Neural stem cell therapy for neuropsychiatric disorders.

OBJECTIVE To conduct a comprehensive literature review of the area of neural stem cells and neuropsychiatry. METHODS 'Neural stem cells' (NSCs) and 'neurogenesis' were used as keywords in Medline (1966 - November 2006) to identify relevant papers in the areas of Alzheimer's disease (AD), depression, schizophrenia and Parkinson's disease (PD). This list was supplemented with papers from refere...

Gut Microbiota and Neuropsychiatric Disorders

Melatonin: A therapeutic potential for the neurohormone in gallbladder disorders

In humans, N-acetyl-5-methoxytryptamine (melatonin), a neurohormone widely found in plants and animal sources, is synthesized from serotonin primarily by the pineal gland. However, it it is also produced in a number of other areas, e.g. the gastrointestinal tract. Melatonin regulates various biological and physiologic body functions and its role in the regulation of circadian rhythms, particula...

Melatonin: A therapeutic potential for the neurohormone in gallbladder disorders

In humans, N-acetyl-5-methoxytryptamine (melatonin), a neurohormone widely found in plants and animal sources, is synthesized from serotonin primarily by the pineal gland. However, it it is also produced in a number of other areas, e.g. the gastrointestinal tract. Melatonin regulates various biological and physiologic body functions and its role in the regulation of circadian rhythms, particula...